Randolph (12-13, 7-9 ODAC) dominated the third quarter in taking the win over Shenandoah (5-20, 2-14).
SU held a 13-6 lead after one and was up 11, 22-11, at the half only to see the WildCats score 19 of the 21 third quarter points to take a lead they would not relinquish.
McKenzie Mathis had the lone Hornets bucket in the stanza, finishing off a layup at 4:47.
The run continued into the fourth with Randolph scoring the initial six points of the period to extend its lead out to 12, 36-24, with 8:38 remaining.
The 'Cats answered with a 6-2 run of their own and coasted home to the 11-point win.
Jacqueline Hockman and Kalyn Banks had 12 and 11 for Randolph, respectively.
Lynchburg is the tournament's top seed.