The two teams kick off the four-team ODAC championship series held at City Stadium in Lynchburg; Roanoke and Virginia Wesleyan complete the four-team field and will meet in a 7:30 contest Friday evening.
Friday's winners play at 3:30 Saturday with the two losers playing an elimination game at noon Saturday.
The winner of the noon contest faces the loser of the 3:30 game at 7.
Sunday's championship game is set for noon.
Shenandoah and R-MC are the two top hitting teams in the ODAC with SU hitting .333 as a team and Macon .330.
Designated hitter Keegan Woolford backs up his .347 average with nine home runs and a league-best 59 RBI.
The Yellow Jackets, who rose to the No. 1 spot in the ABCA poll last week, have six players hitting over .300 who have also made at least 100 at-bats this spring.
Outfielders Ryan Duphorn and Cole Migliorini lead this group with .384 and .383 averages, respectively.
Colin Selby and Nick Roth are Macon's top two starters with Selby posting a 10-1 record with a 2.63 ERA and Roth 9-1 and a 3.18 ERA.
Selby leads the league with 105 strikeouts.
For fans unable to make the trip to Lynchburg, live stats and video will be offered all games of the tournament.