Shenandoah (17-5, 6-3 ODAC) hosts Macon (19-4-1, 6-4) in a double-dip between the two teams picked at the top of the ODAC pre-season poll.
The Hornets and Yellow Jackets have split their last four meetings, with R-MC rallying for an 8-6 win in game one of the March 29, 2015 doubleheader and SU taking the nightcap 5-2.
Thompson, the 2014 ODAC Pitcher of the Year, is 4-1 on the season with 38 strikeouts and a 2.73 ERA in 33.0 innings pitched.
Scimanico is 2-1 on the year with 50 strikeouts in 37.0 innings pitched.
Macon will likely counter with senior James Walsh and sophomore Rick Spiers as its two starters Saturday afternoon.
Walsh (6-0) leads the league in both wins and strikeouts (57) while boasting a 1.49 ERA in 48.1 innings pitched.
Spiers (2-3) has the 'Jackets lone complete game on the year, a 14-1 five-inning victory over Rensselaer on April 21.
SU and R-MC are the two top hitting teams in the ODAC with Macon hitting .317 as a team and Shenandoah .314.
The Hornets 2.62 team ERA is No. 1 in the ODAC to the 'Jackets fifth-best 3.63.
For fans unable to attend the game, live stats are available here.