The win is the lucky 13th of the season for SU (13-5, 7-1 USA South) and also clinches a top two seed at the upcoming USA South Conference Tournament.
Shenandoah, which will play for the regular season title tomorrow at Christopher Newport in a 7 p.m. contest against the Captains, will host either Meredith or N.C. Wesleyan on Tuesday at 7 in the quarterfinal round of the tournament.
The tournament semi-finals and finals are Friday and Saturday in Martinsville.
The 13th win breaks the program record of 12 set in 1998.
The Hornets wasted little time in jumping on the Squirrels (5-9, 1-8), scoring their first goal on an unassisted tally by senior Kat Terza in the fourth minute.
Terza, normally the team's starting goalkeeper, was one of four seniors honored prior to the contest.
Shenandoah added seven more goals in the first half, scoring in the 14th, 15th, 19th, 22nd (twice), 41st and 43rd minutes to take an 8-0 advantage into the break.
The final goal of the half, by Nikki Pursun in the 43rd minute, was the final goal until Sam Butrym scored unassisted with 11 seconds remaining in the contest.
SU was dominant the entire night, outshooting MBC 35-6 and winning five of six corner kicks.
Plourde had two of the team's goals in the first half as she started the game at midfield.
MBC keeper Samantha Thomas had 13 saves.