Shenandoah (5-6, 2-2 ODAC) wasted little time in jumping on Hollins (0-6, 0-5) in rainy conditions on the Sprint Field at Shentel Stadium turf.
SU scored seven goals in the opening 8:55 of the contest with five different women finding the back of the net during this opening run.
Senior Samantha Donaghy, who led all players with five goals, had a hat trick as the hosts quickly took total control of the contest.
Coach Lindsey Lutz' club then elected to play possession lacrosse for the remainder of the half and scored three goals in the final 5:59 of the stanza.
Shenandoah outshot HU 24-5, had a 10-6 advantage in groundballs and won 14 of 21 draw controls.
Eight different women registered at least one point with Liz Bereit pacing this group with three goals and four assists for seven points.
In addition to Donaghy's five goals, freshman Becky Bove had four goals and one assist.
Ashley Cross had to make just three saves, none of them difficult, to post her fourth career shutout.
SU is back in action on Wednesday at 4 p.m. in an ODAC contest against Bridgewater.